CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Aurora kinase A and Potassium voltage-gated channel subfamily H member 2 ligand AGN-PC-08006A family
No. of Seeds 8 No. of Other Members 7
Family Centroid CFAMM00314421 Functional Category Bioactive
Superfamily Aurora kinase A and GABA theta subunit Binder Superfamily
Class Class 1228

Cousin Family NamesSeedsMembers
Adenosine receptor A2b Ligand CVT-6694 Family 1 22
Potassium voltage-gated channel subfamily H member 2 and Vascu... 1 10
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 10 23
Vascular endothelial growth factor receptor 1 and Vascular end... 11 38
Glycogen synthase kinase-3 beta inhibitor 2-(furan-3-yl)-N-[2-... 3 3
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 1 0
Tyrosine-protein kinase JAK2 and Cytochrome P450 1A2 inhibitor... 1 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 11 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 1
Neuronal acetylcholine receptor subunit alpha-4 ligand AGN-PC-... 2 2
Adenosine receptor A2b and Adenosine receptor A1 ligand 8-[1-[... 1 1


External ID

Functional Category

Molecule Name

CFAMM00314423 CHEMBL2203764 Bioactive 3-[[4-[6-chloro-2-(3-cyclopropyl-1-methylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]methyl]-5-methyl-1,2-oxazole
CFAMM00314422 CHEMBL2203767 Bioactive 3-[[4-[6-chloro-2-[4-(4-ethylpiperazin-1-yl)phenyl]-1H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]methyl]-5-methyl-1,2-oxazole
CFAMM00314421 CHEMBL1651456 Bioactive AGN-PC-08006A
CFAMM00314425 CHEMBL1086584 Bioactive AGN-PC-07ZG5W
CFAMM00314418 CHEMBL1651458 Bioactive AGN-PC-08009H
CFAMM00314424 CHEMBL1086582 Bioactive AGN-PC-07ZG5U

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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