CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6992
Family Name D(2) dopamine receptor and D(1A) dopamine receptor ligand ISOMOLPAN family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00325447 Functional Category Bioactive with Natural Product
Superfamily Menin and Cytochrome P450 2D6 Binder Superfamily
Class Class 142

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Alpha-1 adrenergic receptor ligand Dextroamphetamine derivativ... 5 29
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
Muscarinic acetylcholine receptor Ligand Methantheline Family 6 8
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
D(3) dopamine receptor Ligand U-99194A Family 7 33
Acolbifene family 10 115
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Oestrogen receptor and Tyrosine-protein phosphatase non-recept... 92 21
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
DNA-dependent protein kinase catalytic subunit Inhibitor 4-mor... 7 54
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Histamine H3 receptor Ligand (r)-1-(2-methoxyphenethyl)-2-meth... 10 27
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
5-hydroxytryptamine receptor 2A Ligand 1-(2,6-dimethoxy-4-meth... 14 3
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 12
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
D(1A) dopamine receptor and D(3) dopamine receptor ligand N,N-... 3 1
Substance-P receptor ligand AGN-PC-02K8FR family 1 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 8
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Estrogen receptor and Estrogen receptor beta ligand (2R,3R,4S)... 3 0
Transporter and 5-hydroxytryptamine receptor 2C ligand CHEMBL1... 5 5
Histamine H3 receptor ligand 1'-cyclobutyl-6-(1-ethylsulfonylp... 7 10
Histamine H3 receptor ligand 1-[4-(1'-cyclobutylspiro[3,4-dihy... 4 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Estrogen receptor and Estrogen receptor beta ligand SureCN3115... 9 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00E... 7 1
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-flu... 2 0
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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