CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6993
Family Name Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 5-(2-chloropyrrol-1-yl)-N-cyclohexyl-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide family
No. of Seeds 6 No. of Other Members 83
Family Centroid CFAMM00376392 Functional Category Bioactive
Superfamily Tyrosine-protein kinase JAK2 and Cannabinoid receptor 2 Binder Superfamily
Class Class 3858

Cousin Family NamesSeedsMembers
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 4 inhibitor Su... 5 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 16
Tyrosine-protein kinase JAK2 inhibitor N-[2-(3-chlorophenyl)-5... 2 11
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 2 19
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 8 0
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 6 1
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 5 10
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 5-(2-... 12 1
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Aurora kinase B and Aurora kinase A inhibitor (2S)-1-[4-[[1-[(... 12 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 12 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
P2X purinoceptor 7 inhibitor SureCN9931311 family 2 0
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Metabotropic glutamate receptor 5 ligand 5-(4-chlorophenyl)-1,... 3 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Cannabinoid receptor 1 ligand AGN-PC-07R6QU family 4 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 1 1
Cannabinoid receptor 1 ligand AGN-PC-07CPJ5 family 9 14
Cannabinoid receptor 1 ligand AGN-PC-07R5TU family 11 0
Cannabinoid receptor 1 ligand AGN-PC-07R6O8 family 5 2
Cannabinoid receptor 1 ligand AGN-PC-07RA6C family 21 2
Cannabinoid receptor 1 ligand AGN-PC-07RA3R family 15 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QS family 5 0
Cannabinoid receptor 1 ligand AGN-PC-07R9T4 family 27 0
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376385 CHEMBL1909848 Bioactive N-cyclohexyl-1-(2,4-dichlorophenyl)-4-methyl-5-(4,5,6,7-tetrahydroisoindol-2-yl)pyrazole-3-carboxamide
CFAMM00376312 CHEMBL1909852 Bioactive N-cyclohexyl-1-(2,4-dichlorophenyl)-5-(2,5-dimethylpyrrol-1-yl)-4-ethylpyrazole-3-carboxamide
CFAMM00376390 CHEMBL1909846 Bioactive N-cyclohexyl-1-(2,4-dichlorophenyl)-5-(2,5-dichloropyrrol-1-yl)-4-methylpyrazole-3-carboxamide
CFAMM00376311 CHEMBL1909850 Bioactive N-cyclohexyl-1-(2,4-dichlorophenyl)-4-ethyl-5-pyrrol-1-ylpyrazole-3-carboxamide
CFAMM00376380 CHEMBL1629731 Bioactive AGN-PC-08W5QP
CFAMM00376392 CHEMBL1909844 Bioactive 5-(2-chloropyrrol-1-yl)-N-cyclohexyl-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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