CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6998
Family Name Metabotropic glutamate receptor 2 ligand AGN-PC-00A1HD family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00376421 Functional Category Bioactive
Superfamily Huntingtin and Prelamin-A/C Binder Superfamily 32
Class Class 913

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Smoothened homolog Inhibitor Vismodegib Family 1 19
Neuromedin-K receptor Ligand SB222200 Family 17 235
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
D(3) dopamine receptor Ligand SB-277011 Family 13 178
ABC294640 family 5 75
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-chlorophenyl)-5-... 2 8
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
Peroxisome proliferator-activated receptor gamma Ligand 2-chlo... 5 19
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Transient receptor potential cation channel subfamily V member... 3 1
Histone deacetylase 3 and Histone deacetylase 6 inhibitor Tria... 20 37
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 3 3
Metabotropic glutamate receptor 2 ligand AGN-PC-09QJ9P family 2 7
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 5 3
Metabotropic glutamate receptor 2 ligand AGN-PC-09QHIM family 2 0
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Metabotropic glutamate receptor 2 ligand 8-[2-(4-fluorophenyl)... 2 3
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376420 CHEMBL1629864 Bioactive SureCN5557296
CFAMM00376421 CHEMBL1629863 Bioactive AGN-PC-00A1HD

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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