CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7007
Family Name Thyroid hormone receptor beta and Thyroid hormone receptor alpha ligand (2S)-2-[[2-[3,5-dibromo-4-(4-hydroxy-3-propan-2-ylphenoxy)phenyl]acetyl]amino]-3-methylbutanoic acid family
No. of Seeds 8 No. of Other Members 14
Family Centroid CFAMM00376497 Functional Category Bioactive
Superfamily Thyroid hormone receptor beta and Thyroid hormone receptor alpha Binder Superfamily 4
Class Class 1998

Cousin Family NamesSeedsMembers
Thyroid hormone receptor alpha ligand thyroid hormone analog L... 10 61
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 8 1
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 3 5


External ID

Functional Category

Molecule Name

CFAMM00376497 CHEMBL236289 Bioactive (2S)-2-[[2-[3,5-dibromo-4-(4-hydroxy-3-propan-2-ylphenoxy)phenyl]acetyl]amino]-3-methylbutanoic acid
CFAMM00376489 CHEMBL391512 Bioactive (2R)-2-[[2-[3,5-dibromo-4-(4-hydroxy-3-propan-2-ylphenoxy)phenyl]acetyl]amino]-3-methylbutanoic acid
CFAMM00376482 CHEMBL440975 Bioactive (2R)-2-[[2-[3,5-dibromo-4-(4-hydroxy-3-propan-2-ylphenoxy)phenyl]acetyl]amino]propanoic acid
CFAMM00376481 CHEMBL236290 Bioactive (2S)-2-[[2-[3,5-dibromo-4-(4-hydroxy-3-propan-2-ylphenoxy)phenyl]acetyl]amino]-2-phenylacetic acid
CFAMM00376480 CHEMBL236291 Bioactive (2R)-2-[[2-[3,5-dibromo-4-(4-hydroxy-3-propan-2-ylphenoxy)phenyl]acetyl]amino]-2-phenylacetic acid
CFAMM00376493 CHEMBL236080 Bioactive AGN-PC-046RKO
CFAMM00376479 CHEMBL163067 Bioactive Dibit compound
CFAMM00376498 CHEMBL391367 Bioactive SureCN4360386

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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