CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7013
Family Name Coagulation factor X and Prothrombin inhibitor AGN-PC-0754DR family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00376550 Functional Category Bioactive
Superfamily Prothrombin and Coagulation factor X Binder Superfamily
Class Class 2076

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Tubulin beta chain Inhibitor DOLASTATIN-10 Family 4 93
Coagulation factor X Inhibitor Phso2-gly-(me-gly)-arg-(2-thiaz... 32 62
Prothrombin inhibitor (3R,6R,8aS)-N-[5-(diaminomethylideneamin... 4 1
Prothrombin inhibitor (6S,8aS)-N-[5-(diaminomethylideneamino)-... 12 10
Prothrombin inhibitor N-[(2S)-3-[(3S)-1-carbamimidoylpiperidin... 4 10
Coagulation factor XI and Prothrombin inhibitor alpha-ketothia... 5 2
Cationic trypsin and Prothrombin inhibitor benzyl N-[(2R)-1-[(... 2 6
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
Coagulation factor X and Prothrombin inhibitor 2-[(3S)-3-benzy... 7 0
Coagulation factor X and Prothrombin inhibitor N-[5-(diaminome... 2 0
Coagulation factor X and Prothrombin inhibitor AGN-PC-0754CL f... 3 0
Prothrombin inhibitor (3R,6S,8aS)-N-[5-(diaminomethylideneamin... 2 3
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 1 0
Prothrombin and Trypsin-1 inhibitor 2-[(2S)-4-benzyl-2-(naphth... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376550 CHEMBL163121 Bioactive AGN-PC-0754DR
CFAMM00376548 CHEMBL432209 Bioactive (6S,8aS)-N-[5-(diaminomethylideneamino)-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]-4-oxo-2-(3-pyridin-2-ylpropanoyl)-1,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-6-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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