CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7032
Family Name 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine receptor 1A ligand 2-methyl-N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-thiazole-4-carboxamide family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00376622 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Ligand Kuanoniamine D Superfamily
Class Class 2909

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Serine/threonine-protein kinase Chk1 inhibitor 2-(1H-indol-5-y... 2 2
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-benzothiop... 4 6
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Gamma-aminobutyric acid receptor subunit alpha-2 and Gamma-ami... 6 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 2
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 1 4
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 13
Coagulation factor X inhibitor SureCN1253902 family 2 0
Metabotropic glutamate receptor 5 ligand 2-(2-pyridin-3-ylethy... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376622 CHEMBL1632218 Bioactive 2-methyl-N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-thiazole-4-carboxamide
CFAMM00376621 CHEMBL1632219 Bioactive AGN-PC-088NZH

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27669 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543