CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7037
Family Name Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2I family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00376660 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 Binder Superfamily 8
Class Class 1350

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Beta-3 adrenergic receptor Ligand Cgp 12177 Family 3 8
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
Inosine-5'-monophosphate dehydrogenase Inhibitor VX-148 Family 2 3
Substance-K receptor Ligand MEN-14933 Family 13 154
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 6
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 2
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2K family 2 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2L family 1 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
Bifunctional epoxide hydrolase 2 inhibitor 1-(1-adamantyl)-3-[... 2 1
Motilin receptor ligand SureCN14564469 family 1 6
Translocator protein inhibitor CHEMBL2332256 family 1 0
C-X-C chemokine receptor type 3 ligand 1-[1-[(9-acetyl-9-azabi... 1 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-(3-methoxy-2-me... 2 4
Motilin receptor ligand 2,2,2-trichloro-N-[(1R)-1-[(3-chloroph... 1 1
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 12
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 0
Sterol O-acyltransferase 1 inhibitor SureCN6152927 family 7 3
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2
C-X-C chemokine receptor type 3 ligand 1-[1-[[(1S,5R)-6,6-dime... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376661 CHEMBL1632483 Bioactive AGN-PC-088O2J
CFAMM00376660 CHEMBL1632482 Bioactive AGN-PC-088O2I
CFAMM00376657 CHEMBL1632479 Bioactive AGN-PC-088OB1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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