CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM705
Family Name 5-hydroxytryptamine receptor 6 ligand AGN-PC-07ZA0N family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00314464 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 Binder Superfamily 2
Class Class 1575

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Indisu... 2 14
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Translocator protein Inhibitor 5-phenyl-6-thia-10b-aza-benzo[e... 1 2
5-hydroxytryptamine receptor 6 ligand N-methyl-1-[(1R)-6-(1H-p... 3 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 10 2
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 8
5-hydroxytryptamine receptor 6 ligand AGN-PC-09QKIN family 2 9
Sodium-dependent serotonin transporter inhibitor SureCN9171444... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
5-hydroxytryptamine receptor 6 ligand SureCN3147604 family 7 6
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
5-hydroxytryptamine receptor 6 and Muscarinic acetylcholine re... 7 3
5-hydroxytryptamine receptor 6 ligand 1-(4-chlorophenyl)sulfon... 8 4
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
5-hydroxytryptamine receptor 6 ligand 1-(5-bromothiophen-2-yl)... 4 0
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 2 0
5-hydroxytryptamine receptor 6 ligand 9-(2-bromophenyl)sulfony... 2 0
5-hydroxytryptamine receptor 6 ligand 3,4-dichloro-N-[3-[[(2R)... 5 0
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 6 0
Cannabinoid receptor 2 ligand 1-(benzenesulfonyl)-N-quinolin-3... 2 2
Thromboxane A2 receptor ligand 3-[5-[(4-chlorophenyl)sulfonyla... 1 0
5-hydroxytryptamine receptor 6 ligand 4-bromo-N-[3-[[(2S)-1-me... 4 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 0
Hepatocyte growth factor receptor ligand AGN-PC-07C4LM family 1 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-07CR3B family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00314464 CHEMBL1086719 Bioactive AGN-PC-07ZA0N

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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