CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7053
Family Name Muscarinic acetylcholine receptor M2 ligand (2R)-1-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-4-(1-ethylsulfonylpiperidin-4-yl)-2-methylpiperazine family
No. of Seeds 10 No. of Other Members 2
Family Centroid CFAMM00376749 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M2 Binder Superfamily 3
Class Class 3235

Cousin Family NamesSeedsMembers
D(3) dopamine receptor Ligand GR-218231 Family 4 17
Pyruvate kinase PKM and Pyruvate kinase PKLR inhibitor AGN-PC-... 7 19
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 13
Muscarinic acetylcholine receptor M2 ligand (2-chlorophenyl)-[... 7 3
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074ITY family 16 0
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 9 4
Muscarinic acetylcholine receptor M2 ligand (2R)-4-cyclohexyl-... 12 0
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 4 0
Muscarinic acetylcholine receptor M2 ligand N-[2-[4-[(3R)-4-[(... 2 0
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 2 0
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 0
Muscarinic acetylcholine receptor M2 ligand 4-[4-[4-(1,3-benzo... 6 3
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 13 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 3 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 2
Muscarinic acetylcholine receptor M2 ligand 4-[2-[4-(1,3-benzo... 10 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-074P5J family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376743 CHEMBL435849 Bioactive (2R)-1-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-4-(1-butylsulfonylpiperidin-4-yl)-2-methylpiperazine
CFAMM00376749 CHEMBL163714 Bioactive (2R)-1-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-4-(1-ethylsulfonylpiperidin-4-yl)-2-methylpiperazine
CFAMM00376742 CHEMBL164705 Bioactive (2R)-1-[(1R)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-4-cyclohexyl-2-methylpiperazine
CFAMM00376741 CHEMBL165375 Bioactive (2R)-1-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-2-methyl-4-(1-propylsulfonylpiperidin-4-yl)piperazine
CFAMM00376747 CHEMBL163887 Bioactive 4-[(3R)-4-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-3-methylpiperazin-1-yl]-N-ethylpiperidine-1-carboxamide
CFAMM00376740 CHEMBL165337 Bioactive 1-[4-[(3R)-4-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-3-methylpiperazin-1-yl]piperidin-1-yl]pentan-1-one
CFAMM00376746 CHEMBL164397 Bioactive (2R)-1-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-2-methyl-4-piperidin-4-ylpiperazine
CFAMM00376739 CHEMBL163658 Bioactive (2R)-4-[1-(benzenesulfonyl)piperidin-4-yl]-1-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-2-methylpiperazine
CFAMM00376745 CHEMBL353842 Bioactive [4-[(3R)-4-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-3-methylpiperazin-1-yl]piperidin-1-yl]-cyclopropylmethanone
CFAMM00376738 CHEMBL349497 Bioactive (2R)-1-[(1S)-1-[4-(1,3-benzodioxol-5-ylsulfonyl)phenyl]ethyl]-4-cyclohexyl-2-methylpiperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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