CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7056
Family Name Muscarinic acetylcholine receptor M2 ligand (2R)-4-cyclohexyl-1-[(1S)-1-[4-(4-methoxyphenyl)sulfonylphenyl]ethyl]-2-methylpiperazine family
No. of Seeds 12 No. of Other Members 0
Family Centroid CFAMM00376757 Functional Category Bioactive
Superfamily D(3) dopamine receptor Ligand GR-218231 Superfamily
Class Class 1431

Cousin Family NamesSeedsMembers
D(3) dopamine receptor Ligand GR-218231 Family 4 17
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-4-[(1S)-1... 3 13
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Muscarinic acetylcholine receptor M2 ligand (2R)-1-[(1S)-1-[4-... 10 2
72 kDa type IV collagenase and Collagenase 3 inhibitor 1-ethyl... 11 5
Histamine H3 receptor ligand SureCN5093910 family 3 16
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 13 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376754 CHEMBL165439 Bioactive (2R)-4-cyclohexyl-1-[[4-(4-methoxyphenyl)sulfonylphenyl]methyl]-2-methylpiperazine
CFAMM00376753 CHEMBL424530 Bioactive (2R)-4-cyclohexyl-1-[(1R)-1-[4-(4-methoxyphenyl)sulfonylphenyl]ethyl]-2-methylpiperazine
CFAMM00376759 CHEMBL307810 Bioactive 1-cyclohexyl-4-[1-[4-(4-methoxyphenyl)sulfinylphenyl]ethyl]piperazine
CFAMM00376752 CHEMBL164762 Bioactive (2R)-1-cyclohexyl-4-[(1R)-1-[4-(4-methoxyphenyl)sulfonylphenyl]ethyl]-2-methylpiperazine
CFAMM00376758 CHEMBL310912 Bioactive AGN-PC-074HLM
CFAMM00376757 CHEMBL163777 Bioactive (2R)-4-cyclohexyl-1-[(1S)-1-[4-(4-methoxyphenyl)sulfonylphenyl]ethyl]-2-methylpiperazine
CFAMM00376756 CHEMBL352739 Bioactive 2-[(2R)-4-cyclohexyl-2-methylpiperazin-1-yl]-2-[4-(4-methoxyphenyl)sulfonylphenyl]acetonitrile
CFAMM00376755 CHEMBL350956 Bioactive (2S)-1-cyclohexyl-4-[(1R)-1-[4-(4-methoxyphenyl)sulfonylphenyl]ethyl]-2-methylpiperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543