CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7074
Family Name ALK tyrosine kinase receptor and Insulin receptor ligand N-[(1R,2R)-2-[[5-chloro-2-[[7-methoxy-3-(2-methoxyethyl)-1,2,4,5-tetrahydro-3-benzazepin-8-yl]amino]pyrimidin-4-yl]amino]cyclohexyl]methanesulfonamide family
No. of Seeds 3 No. of Other Members 20
Family Centroid CFAMM00376935 Functional Category Bioactive
Superfamily ALK tyrosine kinase receptor and Insulin receptor Binder Superfamily
Class Class 831

Cousin Family NamesSeedsMembers
AP26113 family 16 90
ALK Inhibitor ASP3026 Family 2 4
ALK tyrosine kinase receptor and Insulin receptor ligand SureC... 7 1
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
ALK tyrosine kinase receptor ligand CHEMBL1946804 family 3 0
ALK tyrosine kinase receptor and Ribosomal protein S6 kinase a... 6 2
ALK tyrosine kinase receptor and Insulin receptor ligand 7-[[5... 4 1
ALK tyrosine kinase receptor and Insulin receptor ligand cerit... 2 0
Dihydrofolate reductase inhibitor 5-[[4-[2-[4-(4-aminophenyl)s... 1 0
Ephrin type-B receptor 4 ligand AGN-PC-077MSC family 4 15


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376936 CHEMBL1642257 Bioactive AGN-PC-09QHYC
CFAMM00376935 CHEMBL1796254 Bioactive N-[(1R,2R)-2-[[5-chloro-2-[[7-methoxy-3-(2-methoxyethyl)-1,2,4,5-tetrahydro-3-benzazepin-8-yl]amino]pyrimidin-4-yl]amino]cyclohexyl]methanesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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