CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7076
Family Name 5-hydroxytryptamine receptor 6 ligand AGN-PC-09QKIN family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00376940 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and Muscarinic acetylcholine receptor M1 Binder Superfamily
Class Class 2554

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Indisu... 2 14
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
NF-kappa-B Inhibitor 9-chloro-5h-6-thia-4,5-diaza-chrysene 6,6... 3 27
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
5-hydroxytryptamine receptor 6 ligand AGN-PC-07ZA0N family 1 3
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 10 2
Cannabinoid receptor 2 ligand 1,1,1-trifluoro-N-[(2S)-6-(1-pyr... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
5-hydroxytryptamine receptor 6 and Muscarinic acetylcholine re... 7 3
5-hydroxytryptamine receptor 6 ligand 1-(4-chlorophenyl)sulfon... 8 4
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 12 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-6-br... 5 1
5-hydroxytryptamine receptor 6 ligand 9-(2-bromophenyl)sulfony... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 5 2
C-X-C chemokine receptor type 2 ligand 1-(benzenesulfonyl)-3-[... 1 2
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
Sodium-dependent serotonin transporter and D(2) dopamine recep... 1 0
5-hydroxytryptamine receptor 6 ligand 3,4-dichloro-N-[3-[[(2R)... 5 0
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 3 3
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 6 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03NCPN family 4 0
Prostaglandin D2 receptor 2 ligand SureCN2516080 family 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 6 ligand 4-bromo-N-[3-[[(2S)-1-me... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376941 CHEMBL1642419 Bioactive AGN-PC-046UZK
CFAMM00376940 CHEMBL1642418 Bioactive AGN-PC-09QKIN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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