CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7079
Family Name Melanin-concentrating hormone receptor 1 ligand 1-[1-(1-methylazetidin-3-yl)-2,3-dihydroindol-5-yl]-4-phenylmethoxypyridin-2-one family
No. of Seeds 5 No. of Other Members 10
Family Centroid CFAMM00376995 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily Neuropeptide S receptor and Inositol monophosphatase 1 Binder Superfamily
Class Class 4089

Cousin Family NamesSeedsMembers
PH-797804 family 6 28
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Mitogen-activated protein kinase 14 inhibitor 3-bromo-1-(2,6-d... 5 11
Mitogen-activated protein kinase 14 inhibitor 3-chloro-1-(2,6-... 2 0
Mitogen-activated protein kinase 14 inhibitor 3-bromo-1-(2,6-d... 2 0
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
Quinolines and Derivatives Metabolite (S)-Edulinine Family 1 3
Quinolines and Derivatives Metabolite Huajiaosimuline Family 1 1


External ID

Functional Category

Molecule Name

CFAMM00376995 CHEMBL1830050 Bioactive 1-[1-(1-methylazetidin-3-yl)-2,3-dihydroindol-5-yl]-4-phenylmethoxypyridin-2-one
CFAMM00376986 CHEMBL1642492 Bioactive AGN-PC-09QHX8
CFAMM00376994 CHEMBL1830051 Bioactive 1-[1-[1-(2-fluoroethyl)azetidin-3-yl]-2,3-dihydroindol-5-yl]-4-phenylmethoxypyridin-2-one
CFAMM00376981 CHEMBL1830049 Bioactive 1-[1-(azetidin-3-yl)-2,3-dihydroindol-5-yl]-4-phenylmethoxypyridin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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