CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM708
Family Name Insulin receptor and Tyrosine-protein kinase Lck ligand AGN-PC-00QBEB family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00314474 Functional Category Bioactive
Superfamily Thrombopoietin receptor and Follicle-stimulating hormone receptor Binder Superfamily
Class Class 170

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Prothrombin Inhibitor Dabigatran Family 7 182
IPI-145 family 2 4
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Estrogen receptor beta and Peroxisome proliferator-activated r... 1 1
Type-2 angiotensin II receptor Ligand L-158282 Family 24 58
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 13
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 1 8
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 1 4
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-07ZDR2 f... 7 33
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07RDWA fa... 1 4
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Prelamin-A/C and Niemann-Pick C1 protein inhibitor CHEMBL13592... 1 16
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 11 0
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 6 1
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 3 4
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Aurora kinase B and Aurora kinase A inhibitor (2S)-1-[4-[[1-[(... 12 4
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 6 0
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 2 2
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)imidazo[1,... 5 3
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 3 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Coagulation factor X inhibitor SureCN8290907 family 2 2
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 1 0
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 20 7
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-04XL74 family 1 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Tyrosine-protein kinase Lck and Tyrosine-protein kinase Lyn in... 1 0
Tyrosine-protein kinase ITK/TSK inhibitor SureCN6632543 family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00314474 CHEMBL1086731 Bioactive AGN-PC-00QBEB

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27047 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543