CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7082
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureCN3231037 family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00377100 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Superfamily 9
Class Class 3108

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
Coagulation factor X Inhibitor Otamixaban Family 9 21
PF-4136309 family 16 27
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Transient receptor potential cation channel subfamily V member... 6 23
Egl nine homolog 2 Inhibitor Pyridine-2,4-dicarboxylic Acid Fa... 2 21
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 22
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4R,... 3 7
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 4 11
C-C chemokine receptor type 2 ligand N-[2-[[(3R)-1-(4-hydroxy-... 4 0
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibi... 3 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 1 0
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Platelet-activating factor receptor ligand SureCN9852997 family 1 1
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377100 CHEMBL452587 Bioactive SureCN3231037
CFAMM00377093 CHEMBL1642599 Bioactive N-[4-(3-amino-3-oxopropyl)-4-pyridin-2-ylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
CFAMM00377099 CHEMBL1642587 Bioactive SureCN5477948
CFAMM00377098 CHEMBL1642602 Bioactive SureCN5480320

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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