CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7083
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureCN5484840 family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00377103 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Prelamin-A/C Binder Superfamily
Class Class 3272

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Haloperidol Family 5 53
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 9
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Malonyl-CoA decarboxylase, mitochondrial inhibitor [4-(1,1,1,3... 6 0
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 4
2-bromo-N-[(2R)-2-hydroxy-2-phenylethyl]-N-methylbenzamide NP ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377102 CHEMBL1642600 Bioactive SureCN5476648
CFAMM00377101 CHEMBL1642601 Bioactive SureCN5485076
CFAMM00377107 CHEMBL1642589 Bioactive N-cyclopropyl-N-[4-(2-hydroxyethyl)-4-phenylcyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
CFAMM00377106 CHEMBL1642588 Bioactive SureCN14341264
CFAMM00377104 CHEMBL1642594 Bioactive N-cyclopropyl-N-[4-(methanesulfonamidomethyl)-4-phenylcyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
CFAMM00377103 CHEMBL1642595 Bioactive SureCN5484840

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26822 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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