CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7088
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-PC-08WTSX family
No. of Seeds 6 No. of Other Members 8
Family Centroid CFAMM00377172 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 Binder Superfamily 8
Class Class 4047

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 2 13
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 2
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor N-... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor 4-... 4 5
Calpain-1 catalytic subunit and Cathepsin B inhibitor (4S)-3-(... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377181 CHEMBL1642841 Bioactive (2R)-N-(5-carbamoyl-2-adamantyl)-3-(2-fluorophenyl)sulfonyl-1,3-thiazolidine-2-carboxamide
CFAMM00377180 CHEMBL1642843 Bioactive (2R)-N-(5-carbamoyl-2-adamantyl)-1-(2-fluorophenyl)sulfonylpyrrolidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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