CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7099
Family Name Carbonic anhydrase 12 and Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) inhibitor SureCN672768 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00298189 Functional Category Bioactive
Superfamily Menin and Huntingtin Binder Superfamily 5
Class Class 3547

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Substance-K receptor Ligand MEN-14933 Family 13 154
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Aromatase Inhibitor 2,3-dimethoxy-4'-amino-trans-stilbene Family 5 12
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Bifunctional epoxide hydrolase 2 inhibitor SureCN2729784 family 3 9
Transient receptor potential cation channel subfamily V member... 3 15
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor SureCN... 2 11
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-[(3... 2 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-[4-[3... 2 0
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-ethylbutanoyl)... 11 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
Melatonin receptor type 1B ligand SureCN8150656 family 2 0
Histamine H3 receptor ligand 1-naphthalen-1-yl-3-[4-(3-pyrroli... 1 0


External ID

Functional Category

Molecule Name

CFAMM00377212 CHEMBL2331767 Bioactive 1-(4-methoxy-2-methylphenyl)-3-[4-(sulfamoylamino)phenyl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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