CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7110
Family Name 5-hydroxytryptamine receptor 3A ligand SureCN8035577 family
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00377309 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 3A Ligand Granisetron Superfamily
Class Class 208

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Saquinavir Family 64 428
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Coagulation factor X Inhibitor SN429 Family 23 100
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 19 12
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 7 19
5-hydroxytryptamine receptor 2A ligand AGN-PC-04RTMN family 7 5
Histamine H3 receptor ligand AGN-PC-04YWRD family 5 13
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 29
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 0
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 18
5-hydroxytryptamine receptor 3A ligand N-[(1S,5S)-9-methyl-9-a... 1 0
5-hydroxytryptamine receptor 3A ligand 1-[3-[[5-(dimethylamino... 1 1
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 4 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Coagulation factor X inhibitor SureCN8169809 family 12 18
5-hydroxytryptamine receptor 4 ligand N-[(1R,5S)-8-[2-hydroxy-... 4 0
Coagulation factor X inhibitor AGN-PC-0749DA family 3 2
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(1-cyanocyclop... 2 1
5-hydroxytryptamine receptor 3A ligand 5-hydroxy-1-methyl-N-[(... 4 2
5-hydroxytryptamine receptor 4 ligand 4-[2-[4-[[(1-propan-2-yl... 1 1
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 1
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 0
Motilin receptor ligand SureCN2768052 family 3 0
Serine/threonine-protein kinase Chk1 inhibitor 5-[(2S)-3-amino... 4 6
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Coagulation factor X inhibitor AGN-PC-046QCP family 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Coagulation factor X inhibitor SureCN5254091 family 5 0
Serine/threonine-protein kinase D1 inhibitor 3-[5-[3-bromo-4-(... 1 1
Apoptosis regulator Bcl-2 and Bcl2-associated agonist of cell ... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377307 CHEMBL1643885 Bioactive SureCN8049926
CFAMM00377304 CHEMBL1643882 Bioactive SureCN8046168
CFAMM00377303 CHEMBL1643881 Bioactive SureCN8049977
CFAMM00377309 CHEMBL1643890 Bioactive SureCN8035577
CFAMM00377308 CHEMBL1643892 Bioactive SureCN8044914

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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