CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7128
Family Name Prostaglandin D2 receptor ligand N-[2-(2,4-dichlorophenyl)ethyl]-6-[3-[difluoro(2H-tetrazol-5-yl)methyl]phenyl]-2-methoxypyrimidin-4-amine family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00377384 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 Superfamily
Class Class 37

Cousin Family NamesSeedsMembers
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Dipeptidyl peptidase 4 inhibitor Aminomethylpyrimidine 1ck family 6 3
Mitogen-activated protein kinase 14 inhibitor 5-[2-(2,6-dichlo... 1 0
Corticotropin-releasing factor receptor 1 ligand SureCN7215846... 4 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 1
Adenosine receptor A1 ligand 3-[(2-chlorophenyl)methyl]-N-cycl... 1 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 17 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 1 1
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(2-c... 2 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-07... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377384 CHEMBL1644206 Bioactive N-[2-(2,4-dichlorophenyl)ethyl]-6-[3-[difluoro(2H-tetrazol-5-yl)methyl]phenyl]-2-methoxypyrimidin-4-amine
CFAMM00377385 CHEMBL1644211 Bioactive N-[2-(2,4-dichlorophenyl)ethyl]-2-methoxy-6-[3-[2-(2H-tetrazol-5-yl)propan-2-yl]phenyl]pyrimidin-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26858 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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