CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7151
Family Name Glucocorticoid receptor and Mineralocorticoid receptor ligand SureCN5496690 family
No. of Seeds 7 No. of Other Members 14
Family Centroid CFAMM00235286 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit alpha-1 Ligand (6-benzylamino-9h-beta-carbolin-3-yl)-methanol Superfamily
Class Class 2748

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
D(2) dopamine receptor Ligand Sertindole Family 3 173
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 2 1 2
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 9 3
Glucocorticoid receptor ligand SureCN5650626 family 17 25
Glucocorticoid receptor and Progesterone receptor ligand [(3R,... 6 2
Glucocorticoid receptor ligand SureCN4198717 family 5 0
Glucocorticoid receptor ligand SureCN4204659 family 2 0
Glucocorticoid receptor and Androgen receptor ligand AGN-PC-0A... 3 0
Glucocorticoid receptor ligand AGN-PC-0A9RHA family 1 2
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family 25 7
CGMP-dependent protein kinase inhibitor AGN-PC-075XJ0 family 9 1
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 2 0
Transporter and Sodium-dependent serotonin transporter inhibit... 2 1
5-hydroxytryptamine receptor 2A ligand (3R,4R)-3-(2-phenyl-1H-... 1 18
Beta-3 adrenergic receptor ligand 3-[2-[[(2R)-2-(3-chloropheny... 1 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 7
D(2) dopamine receptor and D(3) dopamine receptor ligand methy... 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (2Z)-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00377594 CHEMBL1644760 Bioactive AGN-PC-00D1JD
CFAMM00377587 CHEMBL1682436 Bioactive SureCN5501547
CFAMM00377585 CHEMBL1682439 Bioactive (3R,4S)-8-chloro-5,7-difluoro-6-(1H-indol-7-yl)-2,2,4-trimethyl-3,4-dihydro-1H-quinolin-3-ol
CFAMM00377596 CHEMBL1762211 Bioactive AGN-PC-0A9Q58

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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