CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7167
Family Name Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5 ligand AGN-PC-077QZS family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00377686 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 5 and Metabotropic glutamate receptor 1 Binder Superfamily
Class Class 4291

Cousin Family NamesSeedsMembers
D(4) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 1
Metabotropic glutamate receptor 1 ligand 4-[1-(2-fluoropyridin... 1 0


External ID

Functional Category

Molecule Name

CFAMM00377687 CHEMBL456196 Bioactive AGN-PC-00EB5E
CFAMM00377680 CHEMBL1645350 Bioactive 4-[1-(2-fluoranylpyridin-3-yl)-5-methyltriazol-4-yl]-N-methyl-N-propan-2-yl-3,6-dihydro-2H-pyridine-1-carboxamide
CFAMM00377686 CHEMBL461673 Bioactive AGN-PC-077QZS
CFAMM00377684 CHEMBL511355 Bioactive AGN-PC-02IQOM
CFAMM00377677 CHEMBL502882 Bioactive FTIDC

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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