CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM717
Family Name Prolyl endopeptidase inhibitor SureCN194654 family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00314547 Functional Category Bioactive with Natural Product
Superfamily Prolyl endopeptidase Inhibitor SUAM-1221 Superfamily
Class Class 634

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 2
Coagulation factor X inhibitor (6S,8aS)-N-[(1-carbamimidoylpip... 6 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 1 1
Sigma non-opioid intracellular receptor 1 ligand (10aS)-2-(2-p... 1 2
Substance-P receptor ligand (3S,4S)-N-[[3,5-bis(trifluoromethy... 8 9
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
Prolyl endopeptidase inhibitor 1-[(4R)-4-(pyrrolidine-1-carbon... 11 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 3 1
Prolyl endopeptidase inhibitor [(2S)-2-(pyrrolidine-1-carbonyl... 3 0
Prolyl endopeptidase inhibitor SureCN8938628 family 2 0
C-C chemokine receptor type 5 ligand N-benzyl-N-[(3R)-1-[(1S,5... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00314548 CHEMBL311472 Bioactive [(2S,3aS,7aS)-2-(1,3-thiazolidine-3-carbonyl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-[(1R,2S)-2-phenylcyclopropyl]methanone
CFAMM00314547 CHEMBL1086968 Bioactive SureCN194654
CFAMM00314550 CHEMBL306119 Bioactive [(1R,2S)-2-phenylcyclopropyl]-[(2S)-2-(1,3-thiazolidine-3-carbonyl)-3-azabicyclo[2.2.2]octan-3-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27668 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543