CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7191
Family Name Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC-08WSN7 family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00284677 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Binder Superfamily 14
Class Class 2579

Cousin Family NamesSeedsMembers
Kinetin family 2 39
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 24 47
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Adenosine receptor A1 and Adenosine receptor A2a Ligand ZM-241... 2 5
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-amin... 3 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 1 0
Adenosine receptor A2a ligand SureCN6867940 family 13 13
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Ferritin light chain and Ras-related protein Rab-9A inhibitor ... 1 11
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
Adenosine receptor A2a ligand 5-N-[[(2R)-1-[(2-chloro-3,6-difl... 7 9
Adenosine receptor A2a ligand 5-[[[(2R)-1-[(2-chloropyridin-4-... 5 0
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Adenosine receptor A2a ligand 7-(3,4-dimethoxyphenyl)-2-(furan... 6 1
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-09ODY0 ... 2 5
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 5
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
Histamine H4 receptor ligand 8-fluoro-4-[(3R)-3-(methylamino)p... 6 1
Scavenger receptor class B member 1 ligand 2-[9-[3-(4,6-dimeth... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 6
Vascular endothelial growth factor receptor 2 and Platelet-der... 16 11
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 0
Adenosine receptor A2a and Adenosine receptor A1 ligand 5-[(7S... 6 1
Adenosine receptor A2a ligand 5-[(7S,9aS)-7-[(2-fluorophenoxy)... 5 4
Vascular endothelial growth factor receptor 2 ligand AGN-PC-04... 8 1
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 25 5
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 29 1
Adenosine receptor A2a and Adenosine receptor A1 ligand 1-[(2-... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 1
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
Muscarinic acetylcholine receptor M1 and Nuclear factor NF-kap... 1 12
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 1 1
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 3 0
Adenosine receptor A2a ligand AGN-PC-02Z2S3 family 3 0
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-03J2ZU f... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 19 2
Adenosine receptor A2a and Adenosine receptor A1 ligand triazi... 3 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 0
Fatty-acid amide hydrolase 1 inhibitor (Z)-1-(4-pyrimidin-4-yl... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377861 CHEMBL508786 Bioactive N-[6-[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-2-(5-methylfuran-2-yl)pyrimidin-4-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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