CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7193
Family Name Dipeptidyl peptidase 4 inhibitor SureCN3389584 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00377876 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 Binder Superfamily 5
Class Class 1189

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Histamine H1 receptor Ligand Triprolidine Family 19 316
Transient receptor potential cation channel subfamily V member... 15 158
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Amg 423 family 7 47
ABC294640 family 5 75
XL-888 family 16 85
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Class II cytokine receptor Ligand IL-10 Family 7 45
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... 3 5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Calcitonin gene-related peptide type 1 receptor Ligand Isomer ... 30 31
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 1 13
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 1 0
Cathepsin K inhibitor SureCN2155973 family 3 1
Reverse transcriptase/RNaseH inhibitor AC1MHDLR family 2 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
Platelet-activating factor receptor ligand YM-461 family 1 11
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 4 8
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
Cell division cycle 7-related protein kinase and Protein DBF4 ... 1 5
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 1 1
Dipeptidyl peptidase 4 inhibitor 2-[[2-[(3R)-3-aminopiperidin-... 1 0
Dipeptidyl peptidase 4 inhibitor 2-[[2-[(3R)-3-aminopiperidin-... 1 0
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 1 0
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-isoquinolin-1-y... 3 2
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... 5 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 0
Histamine H3 receptor ligand [1-[(2-aminopyridin-4-yl)methyl]-... 7 0
Histamine H3 receptor ligand [1-[(2-aminopyridin-4-yl)methyl]-... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 2 2
Platelet-activating factor receptor ligand SureCN9853140 family 3 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 7 2
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377876 CHEMBL1650420 Bioactive SureCN3389584
CFAMM00377879 CHEMBL1650429 Bioactive SureCN3388711

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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