CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7198
Family Name Transient receptor potential M8 protein ligand (3E)-3-[5-[2-(trifluoromethoxy)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00377903 Functional Category Bioactive
Superfamily Histamine H4 receptor and Histone-arginine methyltransferase CARM1 Binder Superfamily
Class Class 1456

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 7-et... 7 57
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Estrogen receptor beta and Estrogen receptor ligand SureCN6442... 1 2
Platelet-derived growth factor receptor alpha and Vascular end... 3 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 11 1
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8
Prostaglandin E synthase inhibitor 2-[6-(2-cyclopropylethoxy)-... 6 0
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377903 CHEMBL1650514 Bioactive (3E)-3-[5-[2-(trifluoromethoxy)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane
CFAMM00377902 CHEMBL1650517 Bioactive (3E)-3-[5-[2-(difluoromethoxy)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane
CFAMM00377905 CHEMBL1650526 Bioactive (3Z)-3-[6-[2-(trifluoromethoxy)phenyl]-4-(trifluoromethyl)benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane
CFAMM00377904 CHEMBL1650520 Bioactive (3E)-3-[5-[2-fluoro-6-(trifluoromethoxy)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26406 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543