CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7199
Family Name Transient receptor potential M8 protein and Cytochrome P450 2C9 ligand (3Z)-3-[4-chloro-6-[2-(trifluoromethyl)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00377909 Functional Category Bioactive
Superfamily Transient receptor potential M8 protein and Cytochrome P450 2C9 Binder Superfamily
Class Class 1983

Cousin Family NamesSeedsMembers
JNJ-39439335 family 5 11
Tryptase Inhibitor Babim Family 12 90
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Neuropeptide Y receptor type 5 and Potassium voltage-gated cha... 6 0
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Transient receptor potential cation channel subfamily M member... 9 0
Transient receptor potential M8 protein and Cytochrome P450 2C... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... 6 12
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00377911 CHEMBL1650532 Bioactive (3Z)-3-[4-chloro-6-[2-(trifluoromethyl)phenyl]benzimidazol-2-ylidene]-1,8-dioxa-2-azaspiro[4.5]decane
CFAMM00377910 CHEMBL1650527 Bioactive (3Z)-3-[6-(2-chlorophenyl)-4-(trifluoromethyl)benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane
CFAMM00377909 CHEMBL1650522 Bioactive (3Z)-3-[4-chloro-6-[2-(trifluoromethyl)phenyl]benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane
CFAMM00377908 CHEMBL1650516 Bioactive (3E)-3-[5-(2-chlorophenyl)benzimidazol-2-ylidene]-1-oxa-2-azaspiro[4.5]decane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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