CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7202
Family Name Tyrosine-protein kinase JAK2 inhibitor SureCN217071 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00378085 Functional Category Bioactive
Superfamily Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 Inhibitor AZD1480 Superfamily
Class Class 1232

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 15 12
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 12
Polycystin-2 and Serine/threonine-protein kinase D1 inhibitor ... 4 12
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 3 11
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 9 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 4
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 1
Protein kinase C theta type and Protein kinase C delta type in... 9 0
Motilin receptor ligand SureCN2004322 family 2 1
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 0
High affinity nerve growth factor receptor ligand SureCN333709... 4 5
High affinity nerve growth factor receptor ligand SureCN490352... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378085 CHEMBL1650698 Bioactive SureCN217071

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27269 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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