CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7224
Family Name Sphingosine 1-phosphate receptor 1 ligand (2R)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]butanoic acid family
No. of Seeds 8 No. of Other Members 35
Family Centroid CFAMM00378247 Functional Category Bioactive
Superfamily Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate receptor 3 Binder Superfamily 3
Class Class 3184

Cousin Family NamesSeedsMembers
Prostaglandin D2 receptor 2 Ligand 2-(2-benzhydryl-4-phenylthi... 14 61
Sphingosine 1-phosphate receptor 1 ligand 3-[3-fluoro-4-[5-(1-... 1 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 4 0
Sphingosine 1-phosphate receptor 1 ligand 1-[[6-ethyl-5-[2-[3-... 3 0
Prostaglandin D2 receptor 2 ligand SureCN5318360 family 4 1
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 2 1
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 3 1


External ID

Functional Category

Molecule Name

CFAMM00378266 CHEMBL1950563 Bioactive 3-[[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methylamino]propanoic acid
CFAMM00378246 CHEMBL1950573 Bioactive (2S)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]butanoic acid
CFAMM00378265 CHEMBL1651861 Bioactive SureCN1661575
CFAMM00378251 CHEMBL1950566 Bioactive 2-[2-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]ethylamino]acetic acid
CFAMM00378241 CHEMBL1950574 Bioactive (2R)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]-2-methylbutanoic acid
CFAMM00378240 CHEMBL1950575 Bioactive (2S)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]-2-methylbutanoic acid
CFAMM00378249 CHEMBL1950481 Bioactive 2-[[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methylamino]acetic acid
CFAMM00378247 CHEMBL1950572 Bioactive (2R)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]butanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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