CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7241
Family Name Pol polyprotein and Renin inhibitor U-75875 family
No. of Seeds 12 No. of Other Members 1
Family Centroid CFAMM00186878 Functional Category Bioactive
Superfamily Pol polyprotein and Renin Binder Superfamily
Class Class 850

Cousin Family NamesSeedsMembers
Epidermal Growth Factor family 111 209
HIV protease Inhibitor Indinavir Family 36 211
Insulin receptor Ligand Insulin, Porcine Family 61 205
Renin Inhibitor Remikiren Family 100 126
Renin Inhibitor Enalkiren Family 56 44
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Plasmepsin-2 Inhibitor KNI-10526 Family 8 10
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 0
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Pol polyprotein inhibitor N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimi... 5 4
Pol polyprotein inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-... 7 3
Renin inhibitor (3R)-4-[[(2S,5S)-1-cyclohexyl-3-hydroxy-6-meth... 3 4
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Collagenase 3 and 72 kDa type IV collagenase inhibitor SureCN3... 1 0
Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0
Pol polyprotein and Protease inhibitor 161186-51-2 family 5 0
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Pol polyprotein inhibitor AC1LAQDX family 3 0
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8
Renin inhibitor SureCN7300793 family 2 5
Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378400 CHEMBL368140 Bioactive (2R,3R,4R)-6-cyclohexyl-3,4-dihydroxy-5-[[3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-ylhexanamide
CFAMM00378406 CHEMBL409073 Bioactive (2S,3S,4S,5S)-6-cyclohexyl-3,4-dihydroxy-N-[(1R)-2-hydroxy-1H-inden-1-yl]-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-2-propan-2-ylhexanamide
CFAMM00378399 CHEMBL2304050 Bioactive (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-[(2S)-3-hydroxy-1-[methyl(pyridin-2-yl)amino]-1-oxopropan-2-yl]-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-2-propan-2-ylhexanamide
CFAMM00378405 CHEMBL1790964 Bioactive (2R,5S)-6-cyclohexyl-3,4-dihydroxy-5-[[3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-ylhexanamide
CFAMM00378398 CHEMBL1790555 Bioactive (2R,3R,4R,5S)-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-7-methyl-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-yloctanamide
CFAMM00378404 CHEMBL2304004 Bioactive (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-[(2S,3R)-3-hydroxy-1-[methyl(pyridin-2-yl)amino]-1-oxobutan-2-yl]-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-2-propan-2-ylhexanamide
CFAMM00378403 CHEMBL1790567 Bioactive (2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-(2-methylpropyl)hexanamide
CFAMM00378402 CHEMBL1790569 Bioactive (2R,3R,4R,5S)-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-7-methyl-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-(2-methylpropyl)octanamide
CFAMM00378401 CHEMBL313256 Bioactive (2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S,3S)-3-methyl-1-[methyl(pyridin-2-yl)amino]-1-oxopentan-2-yl]-2-propan-2-ylhexanamide
CFAMM00378407 CHEMBL1790065 Bioactive (2S,5S)-4-hydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-phenoxyacetyl)amino]propanoyl]amino]-7-methyl-N-[(2S,3R)-3-methyl-1-[methyl(pyridin-2-yl)amino]-1-oxopentan-2-yl]-2-propan-2-yloctanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26843 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543