CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7251
Family Name Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3 ligand N,N'-bis[6-(furan-2-ylmethylamino)hexyl]octane-1,8-diamine family
No. of Seeds 2 No. of Other Members 19
Family Centroid CFAMM00298644 Functional Category Bioactive with Human Metabolite
Superfamily Retinal dehydrogenase 1 and Nonstructural protein 1 Binder Superfamily 2
Class Class 2808

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-317920 Family 9 240
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 2
Fatty-acid amide hydrolase 1 Inhibitor Furan-2-ylmethylcarbami... 1 105
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 1 14
Prelamin-A/C inhibitor CHEMBL1330545 family 1 18
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1424193 family 1 0
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 3 19
Muscarinic acetylcholine receptor M5 and Muscarinic acetylchol... 1 4
Acetylcholinesterase inhibitor 2-[1-[2-[[5-(3,6-dihydro-2H-pyr... 3 9
Arachidonate 5-lipoxygenase inhibitor Urea, N-hydroxy-N-[1-(5-... 2 1
Putative NP ZINC19323106 Family 12 0


External ID

Functional Category

Molecule Name

CFAMM00378493 CHEMBL170793 Bioactive N,N'-bis[6-[(5-methylfuran-2-yl)methylamino]hexyl]octane-1,8-diamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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