CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7262
Family Name Rho-associated protein kinase 1 and Rho-associated protein kinase 2 inhibitor 6-[(3S)-piperidin-3-yl]oxy-2H-isoquinolin-1-one family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00378565 Functional Category Bioactive
Superfamily Caspase-3 and Histamine H3 receptor Binder Superfamily
Class Class 893

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Growth hormone secretagogue receptor type 1 ligand 2-(2-acetyl... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378565 CHEMBL1667967 Bioactive 6-[(3S)-piperidin-3-yl]oxy-2H-isoquinolin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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