CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7269
Family Name Glucocorticoid receptor ligand 2,4,6-trimethyl-N-[(2S)-1-[[6-methyl-1-[3-(propan-2-ylamino)phenyl]indazol-4-yl]amino]propan-2-yl]benzenesulfonamide family
No. of Seeds 16 No. of Other Members 1
Family Centroid CFAMM00378627 Functional Category Bioactive
Superfamily Glucocorticoid receptor Binder Superfamily 3
Class Class 4538

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
E7820 family 9 56
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Protein kinase C theta type and Protein kinase C delta type in... 7 17
Glucocorticoid receptor ligand N-[(3S)-3-[1-(4-fluorophenyl)in... 11 24
Progesterone receptor and Mineralocorticoid receptor ligand AG... 6 1
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 1
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
Glucocorticoid receptor ligand N-ethyl-4-fluoro-N-[3,3,3-trifl... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378624 CHEMBL1668073 Bioactive N-[(2S)-1-[[1-[4-(cyclopropylamino)phenyl]-6-methylindazol-4-yl]amino]propan-2-yl]-2,4,6-trimethylbenzenesulfonamide
CFAMM00378617 CHEMBL1668066 Bioactive N-[(2S)-1-[[1-(3-fluorophenyl)-6-methylindazol-4-yl]amino]propan-2-yl]-2,4,6-trimethylbenzenesulfonamide
CFAMM00378623 CHEMBL1668072 Bioactive 2,4,6-trimethyl-N-[(2S)-1-[[6-methyl-1-[4-(propan-2-ylamino)phenyl]indazol-4-yl]amino]propan-2-yl]benzenesulfonamide
CFAMM00378616 CHEMBL1668064 Bioactive N-[(2S)-1-[[1-(4-fluorophenyl)-6-methylindazol-4-yl]amino]propan-2-yl]-2,4,6-trimethylbenzenesulfonamide
CFAMM00378629 CHEMBL1668075 Bioactive (2R)-2-[4-[6-methyl-4-[[(2S)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propyl]amino]indazol-1-yl]anilino]propanamide
CFAMM00378622 CHEMBL1668079 Bioactive 2-[3-[6-methyl-4-[[(2S)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propyl]amino]indazol-1-yl]anilino]acetamide
CFAMM00378615 CHEMBL1668065 Bioactive N-[(2R)-2-[[1-(4-fluorophenyl)-6-methylindazol-4-yl]amino]propyl]-2,4,6-trimethylbenzenesulfonamide
CFAMM00378628 CHEMBL1668074 Bioactive 2-[4-[6-methyl-4-[[(2S)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propyl]amino]indazol-1-yl]anilino]acetamide
CFAMM00378621 CHEMBL1668078 Bioactive N-[(2S)-1-[[1-[3-(cyclopropylamino)phenyl]-6-methylindazol-4-yl]amino]propan-2-yl]-2,4,6-trimethylbenzenesulfonamide
CFAMM00378614 CHEMBL1668068 Bioactive N-[(2S)-1-[[1-(4-cyanophenyl)-6-methylindazol-4-yl]amino]propan-2-yl]-2,4,6-trimethylbenzenesulfonamide
CFAMM00378627 CHEMBL1668077 Bioactive 2,4,6-trimethyl-N-[(2S)-1-[[6-methyl-1-[3-(propan-2-ylamino)phenyl]indazol-4-yl]amino]propan-2-yl]benzenesulfonamide
CFAMM00378620 CHEMBL1668080 Bioactive (2R)-2-[3-[6-methyl-4-[[(2S)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propyl]amino]indazol-1-yl]anilino]propanamide
CFAMM00378613 CHEMBL1668069 Bioactive 2,4,6-trimethyl-N-[(2S)-1-[[6-methyl-1-(4-methylsulfonylphenyl)indazol-4-yl]amino]propan-2-yl]benzenesulfonamide
CFAMM00378626 CHEMBL1668076 Bioactive (2S)-2-[4-[6-methyl-4-[[(2S)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propyl]amino]indazol-1-yl]anilino]propanamide
CFAMM00378619 CHEMBL1668081 Bioactive (2S)-2-[3-[6-methyl-4-[[(2S)-2-[(2,4,6-trimethylphenyl)sulfonylamino]propyl]amino]indazol-1-yl]anilino]propanamide
CFAMM00378625 CHEMBL1668071 Bioactive 2,4,6-trimethyl-N-[(2S)-1-[[6-methyl-1-[4-(methylamino)phenyl]indazol-4-yl]amino]propan-2-yl]benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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