CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7270
Family Name Glucocorticoid receptor ligand N-(2-amino-2-oxoethyl)-3-[4-[[(2S)-2-(cyclopropylsulfonylamino)propyl]amino]-6-methylindazol-1-yl]benzamide family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00378635 Functional Category Bioactive
Superfamily Plasminogen and Plasma kallikrein Binder Superfamily
Class Class 189

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Glucocorticoid receptor ligand N-ethyl-2-fluoro-N-[3,3,3-trifl... 16 7


External ID

Functional Category

Molecule Name

CFAMM00378631 CHEMBL1668088 Bioactive N-[(2S)-1-amino-1-oxopropan-2-yl]-3-[4-[[(2S)-2-(cyclopropylsulfonylamino)propyl]amino]-6-methylindazol-1-yl]benzamide
CFAMM00378637 CHEMBL1668085 Bioactive 3-[6-methyl-4-[[(2S)-2-(propan-2-ylsulfonylamino)propyl]amino]indazol-1-yl]-N-propan-2-ylbenzamide
CFAMM00378630 CHEMBL1668089 Bioactive N-[(2R)-1-amino-1-oxopropan-2-yl]-3-[4-[[(2S)-2-(cyclopropylsulfonylamino)propyl]amino]-6-methylindazol-1-yl]benzamide
CFAMM00378636 CHEMBL1668086 Bioactive 3-[4-[[(2S)-2-(cyclopropylsulfonylamino)propyl]amino]-6-methylindazol-1-yl]-N-propan-2-ylbenzamide
CFAMM00378635 CHEMBL1668087 Bioactive N-(2-amino-2-oxoethyl)-3-[4-[[(2S)-2-(cyclopropylsulfonylamino)propyl]amino]-6-methylindazol-1-yl]benzamide
CFAMM00378632 CHEMBL1668090 Bioactive N-[(2R)-1-amino-1-oxopropan-2-yl]-3-[4-[[(2S)-2-(cyclopropylsulfonylamino)propyl]amino]-6-methylindazol-1-yl]-N-methylbenzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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