CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7271
Family Name Bile acid receptor and Potassium voltage-gated channel subfamily H member 2 ligand SureCN3568785 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00378638 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 Binder Superfamily
Class Class 1016

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Prothrombin Inhibitor Dabigatran Family 7 182
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
BIBT986 family 7 96
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
SB989 family 17 91
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Cannabinoid receptor 1 Ligand 1-(4-chlorophenyl)-2-(2,4-dichlo... 18 41
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 1 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Lysosomal Pro-X carboxypeptidase inhibitor 2-amino-N-[(2S)-1-[... 11 16
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Bile acid receptor ligand 4-[[(2S)-2-[2-(4-chlorophenyl)-5,6-d... 4 12
Histamine H4 receptor ligand (2Z)-5-chloro-2-[(1-methylpiperid... 2 8
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
C-C chemokine receptor type 5 ligand [4-[2-[3-(2-ethylbenzimid... 5 12
Cannabinoid receptor 1 ligand SureCN675796 family 5 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Coagulation factor X inhibitor SureCN8289965 family 4 5
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Sodium- and chloride-dependent glycine transporter 1 and Sodiu... 4 8
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Substance-P receptor ligand SureCN7659714 family 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-... 12 16
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Substance-K receptor ligand SureCN9035669 family 10 5
Nitric oxide synthase, inducible inhibitor N-[(4-chlorophenyl)... 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
B1 bradykinin receptor ligand AGN-PC-077LWO family 2 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 0
Sonic hedgehog protein and Cytochrome P450 2C9 inhibitor AGN-P... 1 0
P2X purinoceptor 7 inhibitor N-[(3-chloro-2-methylphenyl)methy... 7 0
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378640 CHEMBL1668257 Bioactive (2S)-2-[2-(4-chlorophenyl)-5,6-difluorobenzimidazol-1-yl]-2-cyclohexyl-N-[2-fluoro-4-(2H-tetrazol-5-yl)phenyl]acetamide
CFAMM00378638 CHEMBL1668238 Bioactive SureCN3568785

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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