CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7275
Family Name 5-hydroxytryptamine receptor 6 ligand SureCN3399354 family
No. of Seeds 7 No. of Other Members 3
Family Centroid CFAMM00378656 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine receptor 2B Binder Superfamily
Class Class 3175

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BIUF2 family 25 11
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 0
5-hydroxytryptamine receptor 6 ligand [3-(benzenesulfonyl)-5-m... 7 1
5-hydroxytryptamine receptor 6 ligand 3-(3-chloro-4-fluorophen... 1 2
5-hydroxytryptamine receptor 6 ligand 3-(benzenesulfonyl)-N,5-... 4 1
5-hydroxytryptamine receptor 6 ligand 3-(3-chlorophenyl)sulfon... 6 0


External ID

Functional Category

Molecule Name

CFAMM00378657 CHEMBL1762568 Bioactive SureCN13016747
CFAMM00378656 CHEMBL1668500 Bioactive SureCN3399354
CFAMM00378655 CHEMBL1668574 Bioactive 3-(4-fluorophenyl)sulfonyl-5,7-dimethyl-2-methylsulfanylpyrazolo[1,5-a]pyrimidine
CFAMM00378661 CHEMBL1668571 Bioactive 3-(3-chlorophenyl)sulfonyl-5,7-dimethyl-2-methylsulfanylpyrazolo[1,5-a]pyrimidine
CFAMM00378660 CHEMBL1668572 Bioactive 3-(3-fluorophenyl)sulfonyl-5,7-dimethyl-2-methylsulfanylpyrazolo[1,5-a]pyrimidine
CFAMM00378653 CHEMBL1668580 Bioactive 3-(3-chloro-4-fluorophenyl)sulfonyl-5,7-dimethyl-2-methylsulfanylpyrazolo[1,5-a]pyrimidine
CFAMM00378659 CHEMBL1668573 Bioactive 3-(4-chlorophenyl)sulfonyl-5,7-dimethyl-2-methylsulfanylpyrazolo[1,5-a]pyrimidine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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