CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7289
Family Name 5-hydroxytryptamine receptor 6 ligand 3-(benzenesulfonyl)-N,5-dimethylpyrazolo[1,5-a]pyrimidin-2-amine family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00378767 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine receptor 2B Binder Superfamily
Class Class 3175

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
Hepatocyte growth factor receptor Ligand SGX523 Family 1 15
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BIUF2 family 25 11
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
5-hydroxytryptamine receptor 6 ligand SureCN3399354 family 7 3
5-hydroxytryptamine receptor 6 ligand [3-(benzenesulfonyl)-5-m... 7 1
5-hydroxytryptamine receptor 6 ligand 3-(3-chloro-4-fluorophen... 1 2
5-hydroxytryptamine receptor 6 ligand 3-(3-chlorophenyl)sulfon... 6 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07CBUP family 2 3
Glucose-dependent insulinotropic receptor ligand 4-({Ethyl-[1-... 6 12
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 2 3
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 3 1
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 15
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Casein kinase II subunit alpha inhibitor 7-(cyclopropylamino)-... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-0CSEAG family 2 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07R77D fa... 2 7
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C9 l... 2 5
Prostaglandin G/H synthase 2 and Cyclooxygenase 2 inhibitor Su... 2 6
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor Su... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378769 CHEMBL1668589 Bioactive 3-(3-chlorophenyl)sulfonyl-N-methylpyrazolo[1,5-a]pyrimidin-2-amine
CFAMM00378768 CHEMBL1668583 Bioactive 3-(benzenesulfonyl)-N-methylpyrazolo[1,5-a]pyrimidin-2-amine
CFAMM00378767 CHEMBL1668585 Bioactive 3-(benzenesulfonyl)-N,5-dimethylpyrazolo[1,5-a]pyrimidin-2-amine
CFAMM00378766 CHEMBL1668586 Bioactive 3-(benzenesulfonyl)-N,7-dimethylpyrazolo[1,5-a]pyrimidin-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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