CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7290
Family Name 5-hydroxytryptamine receptor 6 ligand 3-(3-chlorophenyl)sulfonyl-N,5,7-trimethylpyrazolo[1,5-a]pyrimidin-2-amine family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00378776 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine receptor 2B Binder Superfamily
Class Class 3175

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BIUF2 family 25 11
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 0
5-hydroxytryptamine receptor 6 ligand SureCN3399354 family 7 3
5-hydroxytryptamine receptor 6 ligand [3-(benzenesulfonyl)-5-m... 7 1
5-hydroxytryptamine receptor 6 ligand 3-(3-chloro-4-fluorophen... 1 2
5-hydroxytryptamine receptor 6 ligand 3-(benzenesulfonyl)-N,5-... 4 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-0CSEAG family 2 1


External ID

Functional Category

Molecule Name

CFAMM00378771 CHEMBL1922638 Bioactive AGN-PC-07PWO7
CFAMM00378776 CHEMBL1668590 Bioactive 3-(3-chlorophenyl)sulfonyl-N,5,7-trimethylpyrazolo[1,5-a]pyrimidin-2-amine
CFAMM00378775 CHEMBL1668596 Bioactive 3-(3-chloro-4-fluorophenyl)sulfonyl-N,5,7-trimethylpyrazolo[1,5-a]pyrimidin-2-amine
CFAMM00378774 CHEMBL1922635 Bioactive AGN-PC-07PWMS
CFAMM00378773 CHEMBL1922616 Bioactive 3-(benzenesulfonyl)-6-chloro-2-N,5-dimethylpyrazolo[1,5-a]pyrimidine-2,7-diamine
CFAMM00378772 CHEMBL1922615 Bioactive AGN-PC-0BIUEY

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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