CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7291
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand SureCN9077628 family
No. of Seeds 4 No. of Other Members 14
Family Centroid CFAMM00378790 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid A receptor Ligand Zolpidem Superfamily
Class Class 96

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Prothrombin Inhibitor Dabigatran Family 7 182
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
Translocator protein Inhibitor Emapunil Family 7 89
BIBT986 family 7 96
JAK Inhibitor Momelotinib Family 33 83
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 5 58
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 1 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 7 7
Platelet-activating factor receptor ligand SureCN9523843 family 4 4
Platelet-activating factor receptor ligand 5-methyl-2-[4-(2-me... 1 2
Smoothened homolog inhibitor SureCN1091571 family 2 2
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 10 37
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 12
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
C-C chemokine receptor type 5 ligand [4-[2-[3-(2-ethylbenzimid... 5 12
Smoothened homolog and Sonic hedgehog protein inhibitor N-cycl... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Histamine H3 receptor ligand SureCN2878688 family 8 1
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 3 4
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Disintegrin and metalloproteinase domain-containing protein 17... 10 4
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 12 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 3
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 2 0
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Egl nine homolog 1 inhibitor 2-[(1,6-diphenylimidazo[4,5-c]pyr... 1 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor Su... 4 0
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 inhibi... 3 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378777 CHEMBL166874 Bioactive SureCN9075246
CFAMM00378790 CHEMBL351822 Bioactive SureCN9077628
CFAMM00378778 CHEMBL49888 Bioactive SureCN9076167
CFAMM00378792 CHEMBL354385 Bioactive SureCN9077237

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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