CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM73
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 inhibitor AGN-PC-00P8GQ family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00306712 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily
Class Class 893

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 0
Ectonucleotide pyrophosphatase/phosphodiesterase family member... 4 10
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 2 6
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 1 3
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-04X9O... 2 1
D(3) dopamine receptor ligand S33084 family 1 1
Reverse transcriptase/RNaseH inhibitor Thiazoloisoindol-5-one ... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00306712 CHEMBL101121 Bioactive AGN-PC-00P8GQ
CFAMM00306714 CHEMBL103442 Bioactive N-hydroxy-2-[(4-phenylphenoxy)methyl]-4-(1,1,3-trioxo-1,2-benzothiazol-2-yl)butanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26393 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543