CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7302
Family Name Prostaglandin E2 receptor EP4 subtype ligand N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-phenylacetamide family
No. of Seeds 22 No. of Other Members 16
Family Centroid CFAMM00378861 Functional Category Bioactive
Superfamily Prostaglandin E2 receptor EP4 subtype and Integrase Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QHF0 family 3 1
Integrase inhibitor AGN-PC-00QS3S family 2 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378872 CHEMBL272363 Bioactive 2-(2,6-dichlorophenyl)-N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]acetamide
CFAMM00378865 CHEMBL218699 Bioactive 2-(2-chlorophenyl)-N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]acetamide
CFAMM00378845 CHEMBL402960 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-(2-fluorophenyl)acetamide
CFAMM00378858 CHEMBL405446 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-1-(2,6-dimethoxyphenyl)cyclopropane-1-carboxamide
CFAMM00378877 CHEMBL1669003 Bioactive 1-[1-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methyl]cyclopropyl]-3-naphthalen-2-ylsulfonylurea
CFAMM00378844 CHEMBL256005 Bioactive N-[[4-(5,9-diethoxy-8-oxo-6H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-phenylacetamide
CFAMM00378870 CHEMBL272571 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-pyridin-4-ylacetamide
CFAMM00378863 CHEMBL256873 Bioactive 2-(2-acetyl-6-methoxyphenyl)-N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]acetamide
CFAMM00378876 CHEMBL402162 Bioactive SureCN1734980
CFAMM00378843 CHEMBL256822 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-1-(2-methoxyphenyl)cyclopropane-1-carboxamide
CFAMM00378856 CHEMBL270397 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-[2-(trifluoromethyl)phenyl]acetamide
CFAMM00378875 CHEMBL269987 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-[2-(trifluoromethoxy)phenyl]acetamide
CFAMM00378861 CHEMBL403630 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-phenylacetamide
CFAMM00378874 CHEMBL257886 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-pyridin-2-ylacetamide
CFAMM00378867 CHEMBL270223 Bioactive 1-(2-methoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]cyclopropane-1-carboxamide
CFAMM00378880 CHEMBL404199 Bioactive 1-(2,6-dimethoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]cyclopropane-1-carboxamide
CFAMM00378847 CHEMBL257255 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-[2-(difluoromethoxy)phenyl]acetamide
CFAMM00378860 CHEMBL1669011 Bioactive AGN-PC-04UDMP
CFAMM00378873 CHEMBL271095 Bioactive 2-(2-methoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]acetamide
CFAMM00378853 CHEMBL444800 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-pyridin-3-ylacetamide
CFAMM00378879 CHEMBL272498 Bioactive 2-(2-methoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-di(propan-2-yloxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]acetamide
CFAMM00378859 CHEMBL255906 Bioactive N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-(2-ethoxyphenyl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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