CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7307
Family Name Substance-K receptor and Substance-P receptor ligand N-[(2Z,3R)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxopiperidin-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide family
No. of Seeds 26 No. of Other Members 4
Family Centroid CFAMM00378923 Functional Category Bioactive
Superfamily Substance-K receptor and Substance-P receptor Binder Superfamily 7
Class Class 4536

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Neuromedin-K receptor Ligand Osanetant Family 38 192
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 1 1
Substance-K receptor and Substance-P receptor ligand N-[4-[[4-... 1 4
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 2 0
Substance-P receptor and Substance-K receptor ligand 3,5-dichl... 7 2
Substance-P receptor and Substance-K receptor ligand 3,5-dichl... 19 0
Prothrombin inhibitor AGN-PC-09QJ23 family 2 5
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 3
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
Substance-K receptor and Neuromedin-K receptor ligand SureCN78... 2 4
Substance-P receptor and Substance-K receptor ligand 2-[3-[1-[... 10 0
Substance-P receptor and Substance-K receptor ligand benzyl 2-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00378906 CHEMBL304106 Bioactive 3,5-dichloro-N-[(2Z,3S)-3-(3,4-dichlorophenyl)-5-[4-[3-[2-(dimethylamino)-2-oxoethyl]-2-oxopiperidin-1-yl]piperidin-1-yl]-2-methoxyiminopentyl]-N-methylbenzamide
CFAMM00378919 CHEMBL76437 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-2-methoxyimino-5-[4-(2-oxo-3-propan-2-yl-1,3-diazinan-1-yl)piperidin-1-yl]pentyl]-N-methylbenzamide
CFAMM00378912 CHEMBL355041 Bioactive N-[(2Z,3R)-2-[(2E)-2-amino-2-hydroxyiminoethoxy]imino-3-(3,4-dichlorophenyl)-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378925 CHEMBL75598 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-2-methoxyimino-5-[4-(3-methyl-2-oxo-1,3-diazinan-1-yl)piperidin-1-yl]pentyl]-N-methylbenzamide
CFAMM00378918 CHEMBL57993 Bioactive 3,5-dichloro-N-[(2Z,3S)-3-(3,4-dichlorophenyl)-2-methoxyimino-5-[4-[3-[2-(methylamino)-2-oxoethyl]-2-oxopiperidin-1-yl]piperidin-1-yl]pentyl]-N-methylbenzamide
CFAMM00378905 CHEMBL67171 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-5-[4-[3-[2-(dimethylamino)-2-oxoethyl]-2-oxopiperidin-1-yl]piperidin-1-yl]-2-methoxyiminopentyl]-N-methylbenzamide
CFAMM00378911 CHEMBL78132 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-5-[4-(3-hydroxy-2-oxo-1,3-diazinan-1-yl)piperidin-1-yl]-2-methoxyiminopentyl]-N-methylbenzamide
CFAMM00378924 CHEMBL308891 Bioactive 3,5-dichloro-N-[(2Z)-3-(3,4-dichlorophenyl)-2-methoxyimino-5-[4-[3-[2-(methylamino)-2-oxoethyl]-2-oxopiperidin-1-yl]piperidin-1-yl]pentyl]-N-methylbenzamide
CFAMM00378904 CHEMBL404599 Bioactive N-[(2Z,3R)-5-[4-[3-[(2Z)-2-amino-2-hydroxyiminoethyl]-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378917 CHEMBL66332 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-2-methoxyimino-5-[4-[3-[2-(methylamino)-2-oxoethyl]-2-oxopiperidin-1-yl]piperidin-1-yl]pentyl]-N-methylbenzamide
CFAMM00378923 CHEMBL441252 Bioactive N-[(2Z,3R)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxopiperidin-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378903 CHEMBL67508 Bioactive N-[(2Z)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxopiperidin-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378929 CHEMBL78284 Bioactive N-[(2Z,3R)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378909 CHEMBL446146 Bioactive 3,5-dichloro-N-[(2Z)-3-(3,4-dichlorophenyl)-5-[4-[3-[2-(dimethylamino)-2-oxoethyl]-2-oxopiperidin-1-yl]piperidin-1-yl]-2-methoxyiminopentyl]-N-methylbenzamide
CFAMM00378922 CHEMBL167606 Bioactive N-[(2Z)-2-(3-aminopropoxyimino)-3-(3,4-dichlorophenyl)-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378902 CHEMBL166921 Bioactive N-[(2Z)-2-[(2E)-2-amino-2-hydroxyiminoethoxy]imino-3-(3,4-dichlorophenyl)-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378915 CHEMBL263243 Bioactive N-[(2Z,3R)-5-[4-[3-[(2R)-1-amino-3-hydroxy-1-oxopropan-2-yl]-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378928 CHEMBL355295 Bioactive 3,5-dichloro-N-[(2Z)-3-(3,4-dichlorophenyl)-2-[3-(methylcarbamoylamino)propoxyimino]-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentyl]-N-methylbenzamide
CFAMM00378921 CHEMBL310273 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-5-[4-[3-(2-hydroxy-2-methylpropyl)-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-2-methoxyiminopentyl]-N-methylbenzamide
CFAMM00378914 CHEMBL74956 Bioactive N-[(2Z,3R)-5-[4-[3-(1-amino-2-methyl-1-oxopropan-2-yl)-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378927 CHEMBL451235 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-2-methoxyimino-5-[4-(3-morpholin-4-yl-2-oxo-1,3-diazinan-1-yl)piperidin-1-yl]pentyl]-N-methylbenzamide
CFAMM00378907 CHEMBL66635 Bioactive N-[(2Z,3S)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxopiperidin-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
CFAMM00378913 CHEMBL77023 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-2-methoxyimino-5-[4-[(3R)-3-[2-(methylamino)-2-oxoethyl]-2-oxopiperidin-1-yl]piperidin-1-yl]pentyl]-N-methylbenzamide
CFAMM00378926 CHEMBL310334 Bioactive 3,5-dichloro-N-[(2Z,3R)-3-(3,4-dichlorophenyl)-2-methoxyimino-5-[4-[3-[2-(methylamino)-2-oxoethyl]-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]pentyl]-N-methylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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