CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7322
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-(4-methoxyphenyl)-2-methylpropanamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00379115 Functional Category Bioactive
Superfamily Retinal dehydrogenase 1 and Huntingtin Binder Superfamily 2
Class Class 516

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 3 5
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 11 9
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00379117 CHEMBL17245 Bioactive N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-(4-methoxyphenyl)benzamide
CFAMM00379115 CHEMBL16700 Bioactive N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-(4-methoxyphenyl)-2-methylpropanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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