CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7367
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-pentylbenzamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00379411 Functional Category Bioactive
Superfamily Androgen receptor and 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Binder Superfamily
Class Class 4547

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Bavisant family 9 65
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Sodium-dependent dopamine transporter and Sodium-dependent nor... 10 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 8
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 18
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
5-hydroxytryptamine receptor 1A ligand U93385 family 4 1
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
C-C chemokine receptor type 5 ligand N-benzyl-N-[(3R)-1-[(1S,5... 1 3
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor N-[(1S,5aR,9... 2 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00379406 CHEMBL276527 Bioactive N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-benzylformamide
CFAMM00379411 CHEMBL16784 Bioactive N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-pentylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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