CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7375
Family Name Corticotropin-releasing factor receptor 1 ligand 4-N-[2-bromo-4-(dimethylamino)phenyl]-4-N-ethyl-6-methyl-2-N,2-N-bis(prop-2-enyl)-1,3,5-triazine-2,4-diamine family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00379469 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Binder Superfamily
Class Class 3062

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 ligand 4-N-(2-bromo-... 9 48
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 2
Cruzipain and Cathepsin K inhibitor AGN-PC-076IFJ family 3 3
Cruzipain and Papain inhibitor AGN-PC-076IFP family 1 0
Cruzipain and Cathepsin K inhibitor SureCN3350907 family 2 0
Cell division cycle 7-related protein kinase inhibitor CHEMBL1... 1 2
Cruzipain and Papain inhibitor AGN-PC-076IFM family 1 1
Cruzipain and Papain inhibitor ST081881 family 1 1


External ID

Functional Category

Molecule Name

CFAMM00379479 CHEMBL566924 Bioactive SureCN3348177
CFAMM00379469 CHEMBL168131 Bioactive 4-N-[2-bromo-4-(dimethylamino)phenyl]-4-N-ethyl-6-methyl-2-N,2-N-bis(prop-2-enyl)-1,3,5-triazine-2,4-diamine
CFAMM00379471 CHEMBL424538 Bioactive 2-N-[2-bromo-4-(dimethylamino)phenyl]-2-N,4-N,4-N-triethyl-6-methyl-1,3,5-triazine-2,4-diamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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