CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7380
Family Name Coagulation factor X inhibitor N-[5-carbamoyl-2-[[(5-chlorothiophene-2-carbonyl)amino]methyl]phenyl]-5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide family
No. of Seeds 8 No. of Other Members 8
Family Centroid CFAMM00379513 Functional Category Bioactive
Superfamily Coagulation factor X Binder Superfamily 4
Class Class 1056

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor IDX899 Family 2 118
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 17 23
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
Coagulation factor X and Prothrombin inhibitor SureCN763988 fa... 31 86
Glycogen phosphorylase, liver form inhibitor 2,3-dichloro-N-[(... 2 14
Coagulation factor X inhibitor 2-[4-[(5-chloro-1H-indole-2-car... 4 0
Coagulation factor X inhibitor 2-carboxyindole 24 family 1 0
Coagulation factor X inhibitor 4-[3-(4-bromoanilino)-3-oxoprop... 2 2
Coagulation factor X inhibitor 4-[[(5-chlorothiophene-2-carbon... 10 8
Coagulation factor X inhibitor 4-[3-(4-chloroanilino)-3-oxopro... 6 1
Peroxisome proliferator-activated receptor alpha ligand SureCN... 3 8
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 5 5
Glycogen phosphorylase, liver form inhibitor SureCN5630210 family 2 0
Coagulation factor X inhibitor SureCN1251046 family 3 0
Coagulation factor X inhibitor SureCN1322298 family 2 1
Coagulation factor X inhibitor N-[(1R,2S,5S)-2-[(5-bromo-1H-in... 1 1
Coagulation factor X inhibitor SureCN1253902 family 2 0
Histamine H4 receptor ligand SureCN605081 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00379509 CHEMBL1923800 Bioactive N-[2-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-5-(methylcarbamoyl)phenyl]-5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
CFAMM00379502 CHEMBL1923871 Bioactive N-[2-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-5-(dimethylcarbamoyl)phenyl]-5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
CFAMM00379508 CHEMBL1923801 Bioactive N-[2-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-6-(dimethylcarbamoyl)phenyl]-5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
CFAMM00379501 CHEMBL1923873 Bioactive N-[2-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-5-(methylsulfonylcarbamoyl)phenyl]-5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
CFAMM00379500 CHEMBL1681798 Bioactive AGN-PC-04UAS3
CFAMM00379513 CHEMBL1923798 Bioactive N-[5-carbamoyl-2-[[(5-chlorothiophene-2-carbonyl)amino]methyl]phenyl]-5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
CFAMM00379512 CHEMBL1923799 Bioactive N-[2-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-6-(methylcarbamoyl)phenyl]-5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
CFAMM00379510 CHEMBL1923797 Bioactive N-[2-carbamoyl-6-[[(5-chlorothiophene-2-carbonyl)amino]methyl]phenyl]-5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Professor in Department of Pharmacy
National University of Singapore, Singapore

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