CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7402
Family Name Prothrombin inhibitor AGN-PC-073H0Z family
No. of Seeds 9 No. of Other Members 6
Family Centroid CFAMM00379764 Functional Category Bioactive
Superfamily Prothrombin and cGMP-specific 3',5'-cyclic phosphodiesterase Binder Superfamily
Class Class 2472

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mepyramine Family 5 65
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Mitogen-activated protein kinase 14 inhibitor N-(4-aminobutyl)... 1 28
Sodium channel protein type 10 subunit alpha and Sodium channe... 3 22
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Prothrombin inhibitor AGN-PC-09QIOA family 6 0
Prothrombin inhibitor AGN-PC-08Y2XS family 3 0
cGMP-specific 3',5'-cyclic phosphodiesterase and Rod cGMP-spec... 42 3
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Transient receptor potential cation channel subfamily V member... 6 1
Prothrombin and Trypsin-1 inhibitor 2-[6-chloro-3-[(2,2-difluo... 1 0
Delta-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 1 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 4
Glutamate receptor ionotropic, NMDA 2B and Cytochrome P450 2D6... 2 3
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 3
9-(4-methoxyphenyl)-5-(3-methylbutanoyl)-6-pyridin-3-yl-8,9,10... 8 0


External ID

Functional Category

Molecule Name

CFAMM00379778 CHEMBL1682757 Bioactive AGN-PC-09QMX3
CFAMM00379768 CHEMBL26213 Bioactive AGN-PC-00KAJR
CFAMM00379767 CHEMBL29181 Bioactive 2-[6-chloro-3-[[2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl]amino]-2-oxopyrazin-1-yl]-N-[[2-(trifluoromethoxy)phenyl]methyl]acetamide
CFAMM00379766 CHEMBL283851 Bioactive AGN-PC-073GXH
CFAMM00379775 CHEMBL286720 Bioactive 2-[6-chloro-3-[[2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl]amino]-2-oxopyrazin-1-yl]-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]acetamide
CFAMM00379765 CHEMBL27180 Bioactive AGN-PC-073GZP
CFAMM00379774 CHEMBL280640 Bioactive AGN-PC-073H1B
CFAMM00379764 CHEMBL29417 Bioactive AGN-PC-073H0Z
CFAMM00379773 CHEMBL1682696 Bioactive AGN-PC-09QGWV

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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