CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7411
Family Name Prothrombin inhibitor AGN-PC-09QLAK family
No. of Seeds 10 No. of Other Members 2
Family Centroid CFAMM00379828 Functional Category Bioactive with Natural Product
Superfamily Prothrombin and Glutamate receptor 1 Binder Superfamily
Class Class 3858

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Prothrombin inhibitor SureCN5855286 family 15 8
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 2
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 ligand AGN-PC-07N4XX family 6 10
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Platelet-activating factor receptor ligand SureCN9523843 family 4 4
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
5-hydroxytryptamine receptor 4 ligand 6-chloro-N-[[1-(2-methyl... 10 19
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 2
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 2 10
Hepatocyte growth factor receptor ligand 5-[(6-phenyl-[1,2,4]t... 6 2
Prothrombin inhibitor 2-[3-cyano-6-(2,2-difluoro-2-pyridin-2-y... 3 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X3N ... 1 7
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
P2X purinoceptor 7 inhibitor SureCN9931311 family 2 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Epithelial discoidin domain-containing receptor 1 and Mast/ste... 1 0
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 10 1
Histone deacetylase 1 and Proto-oncogene tyrosine-protein kina... 4 0
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Thromboxane-A synthase inhibitor 6-chloro-3-(4-imidazol-1-ylbu... 12 21
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Sonic hedgehog protein and Cytochrome P450 2C9 inhibitor AGN-P... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00379834 CHEMBL1682788 Bioactive AGN-PC-09QGX8
CFAMM00379827 CHEMBL1682784 Bioactive AGN-PC-09QLJV
CFAMM00379833 CHEMBL1682783 Bioactive AGN-PC-09QLAJ
CFAMM00379832 CHEMBL1682782 Bioactive AGN-PC-09QJIP
CFAMM00379824 CHEMBL1682776 Bioactive AGN-PC-09QMX6
CFAMM00379831 CHEMBL1682781 Bioactive AGN-PC-08Y2XW
CFAMM00379823 CHEMBL1682777 Bioactive AGN-PC-08Y2XV
CFAMM00379830 CHEMBL1682787 Bioactive AGN-PC-09QM3L
CFAMM00379829 CHEMBL1682786 Bioactive AGN-PC-09QMX8
CFAMM00379828 CHEMBL1682785 Bioactive AGN-PC-09QLAK

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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