CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7414
Family Name Glycogen synthase kinase-3 beta inhibitor 6-[(2S)-2-(2-methoxyphenyl)morpholin-4-yl]-1-methyl-4-pyrimidin-4-ylpyridin-2-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00379847 Functional Category Bioactive
Superfamily Huntingtin and Arachidonate 15-lipoxygenase Binder Superfamily
Class Class 850

Cousin Family NamesSeedsMembers
AP26113 family 16 90
SB1518 family 7 103
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 10
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
Hepatocyte growth factor receptor Ligand BMS-777607 Family 10 1
Mitogen-activated protein kinase 14 Inhibitor Pamapimod Family 15 7
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 1 7
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 0
Inositol monophosphatase 1 inhibitor CHEMBL1588383 family 1 6
Glycogen synthase kinase-3 beta inhibitor AGN-PC-0802SH family 1 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 7 6


External ID

Functional Category

Molecule Name

CFAMM00379847 CHEMBL1682851 Bioactive 6-[(2S)-2-(2-methoxyphenyl)morpholin-4-yl]-1-methyl-4-pyrimidin-4-ylpyridin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



112719 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543